20,017 research outputs found
Learning to Translate in Real-time with Neural Machine Translation
Translating in real-time, a.k.a. simultaneous translation, outputs
translation words before the input sentence ends, which is a challenging
problem for conventional machine translation methods. We propose a neural
machine translation (NMT) framework for simultaneous translation in which an
agent learns to make decisions on when to translate from the interaction with a
pre-trained NMT environment. To trade off quality and delay, we extensively
explore various targets for delay and design a method for beam-search
applicable in the simultaneous MT setting. Experiments against state-of-the-art
baselines on two language pairs demonstrate the efficacy of the proposed
framework both quantitatively and qualitatively.Comment: 10 pages, camera read
The key position: influence of staple location on constrained peptide conformation and binding
First published online 29 Sep 2016Constrained α-helical peptides are showing potential as biological probes and therapeutic agents that target protein-protein interactions. However, the factors that determine the optimal constraint locations are still largely unknown. Using the β-integrin/talin protein interaction as a model system, we examine the effect of constraint location on helical conformation, as well as binding affinity, using circular dichroism and NMR spectroscopy. Stapling increased the overall helical content of each integrin-based peptide tested. However, NMR analysis revealed that different regions within the peptide are stabilised, depending on constraint location, and that these differences correlate with the changes observed in talin binding mode and affinity. In addition, we show that examination of the atomic structure of the parent peptide provides insight into the appropriate placement of helical constraints.Kelly L. Keeling, Okki Cho, Denis B. Scanlon, Grant W. Booker, Andrew D. Abell and Kate L. Wegene
Filler wire for aluminum alloys and method of welding
A weld filler wire chemistry has been developed for fusion welding 2195 aluminum-lithium. The weld filler wire chemistry is an aluminum-copper based alloy containing high additions of titanium and zirconium. The additions of titanium and zirconium reduce the crack susceptibility of aluminum alloy welds while producing good weld mechanical properties. The addition of silver further improves the weld properties of the weld filler wire. The reduced weld crack susceptibility enhances the repair weldability, including when planishing is required
Fabrication technologies for quantum cascade photonic-crystal microlasers
In this paper we describe the technological and fabrication methods necessary to incorporate both photonic and electronic-band engineering in order to create novel surface-emitting quantum cascade microcavity laser sources. This technology offers the promise of several innovative applications such as the miniaturization of QC lasers, and multi-wavelength two-dimensional laser arrays for spectroscopy, gas-sensing and imaging. This approach is not limited to light-emitting devices, and may be efficiently applied to the development of mid- and far-infrared normal-incidence detectors
Supersymmetric Gauge Theories with an Affine Quantum Moduli Space
All supersymmetric gauge theories based on simple groups which have an affine
quantum moduli space, i.e. one generated by gauge invariants with no relations,
W=0, and anomaly matching at the origin, are classified. It is shown that the
only theories with no gauge invariants (and moduli space equal to a single
point) are the two known examples, SU(5) with 5-bar + 10 and SO(10) with a
spinor. The index of the matter representation must be at least as big as the
index of the adjoint in theories which have a non-trivial relation among the
gauge invariants.Comment: Incorrect proof that theories with constraints must have mu >=
mu(adj) replaced by a correct one (6 pages, uses revtex, amssymb, array
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